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Avandamet® (rosiglitazone maleate/metformin HCl) is a new prescription medicine for treatment of type 2 diabetes. It is a single pill combining two popular diabetes medications. Avandamet® combines Rosiglitazone, known individually as Avandia® and Metformin HCl in a single pill to provide the combined action of the two medications in an easy to administer single dose. The two medications work in different ways to help patients who are being treated for type 2 diabetes. Rosiglitazone is said to make the body’s own insulin perform better, while Metformin HCl acts by lowering the liver’s production of sugar. Metformin HCl is the generic name of Glucophage®, and is a well known and widely accepted treatment for type 2 diabetes. Rosiglitazone maleate is the drug known more popularly as Avandia®, and it too is widely accepted for type 2 diabetes

It is common for endocrinologists to prescribe either or both drugs along with diet and exercise as parts of a comprehensive treatment of type 2 diabetes, and Avandamet® is a prescription medication, which doctors might prefer to prescribe for patients who would otherwise be receiving both medications as part of their treatment.

Taking Avandamet® can cause or exacerbate fluid retention problems and can lead to weight gain, as well as heart problems. This new formulation contains Metformin therefore the warning about occasional reactions to the use of Metformin, including the possibility of developing lactic acidosis, which can be fatal, is repeated in the warnings pertaining to this medication. Additionally, a warning appears on the website stating that taking Avandamet® may cause heart failure. Avandament®, like all drugs for the control of diabetes type 2 requires monitoring of blood sugar as well as other health markers including liver and kidney function. As with all
prescription medications, always consult with your doctor for more information.


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