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Imitrex is a drug for headaches. It was especially designed to treat migraines and headaches.

How it works

Imitrex works by narrowing blood vessels around the brain. This reduces the blood flow rate to the brain. It also removes or reduces substances in the body that can trigger headaches, nausea as well as sensitivity to light and sound. Imitrex cannot prevent headaches or migraine; it only cures existing migraine without causing drowsiness.

Forms of medication

Imitrex comes in the form of tablets, nasal spray and as injection.


Use Imitrex exactly to the instructions on the label or as prescribed by a doctor. Don’t use smaller or larger than prescribed amounts or for longer than recommended. Imitrex should be taken as soon as headache or migraine is noticed. Take Imitrex with a full glass of water. Do not split the tablet. After taking a tablet, if the migraine persists or returns another can be taken only after at least
two hours. Unless advised by a doctor, do not take above 200mg of Imitrex a day.

Before using the nasal spray, blow nose to clear nasal passages. Do not sneeze or blow nose just after using the nasal spray. If after use the headache persist or returns, another nasal spray can be used only after two hours from the first. Unless as advised by a doctor, do not use more than 40mg of nasal spray under 24 hours. If symptoms persist or don’t approve consult your doctor before increasing your dose.

Side effects

The most common side effects of Imitrex are tingling and warm/cold sensations (Tablets), a bad/unusual taste (Nasal Spray), and injection-site reactions, atypical sensations (such as feelings of tingling, warm/hot sensations), dizziness, and flushing (Injection). Most side effects last for only a short time.

Imitrex can cause serious side effects on the heart, including heart attack or stroke. Although these side effects are rare, do not use this medication if you have a history of heart disease, angina (chest pain), blood circulation problems, ischemic bowel disease, severe or uncontrolled high blood pressure, or history of a heart attack or stroke.

Before using Imitrex, tell your doctor if you have a seizure disorder, coronary artery disease, or risk factors for coronary artery disease (such as diabetes, menopause, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease, being older than 40
and a man, or being a woman who has had a hysterectomy).


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