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Pamabrom is seldom used by itself, and is actually considered an obsolete drug. It is a bromotheophylline compound with 2-amino-2-methyl-1-propanol. otherwise described as a diuretic that reduces bloating as a result of water retention. However, in combination with acetaminophen as a pain reliever, it is a highly popular product especially targeted for menstruating women.

Information you should know

Premenstrual syndrome (PMS) and menstruation are usually accompanied by bloating and cramps, which makes pamabrom in combination with acetaminophen an ideal over-the-counter medication. This duo has been marketed as Women’s Tylenol Menstrual Relief, Midol Maximum Strength Teen, Formula, Pamprin Maximum Strength Menstrual Pain Relief Multi-Symptom and Women’s Tylenol Menstrual Relief Caplets, but they are also available as generic preparations. It provides temporarily relief from premenstrual and menstrual cramps, headaches, and backaches. It also reduces water-weight gain and swelling usually resulting from PMS and menstrual periods. Some formulations may also contain hydroxyproyl methylcellulose, sodium, starch glycolate, titanium dioxide, triacetin, cornstarch and cellulose. It may produce excitability in children.

Directions for taking Pamabrom

While it is available over-the-counter, it is important that a physician is consulted before taking the medication, especially if other medications have been prescribed. Possible interactions may occur with medications such as blood-thinning drugs (e.g. Coumadin), diabetes drugs (e.g. Orinase), gout medications (e.g. Zyloprim) and arthritis drugs (e.g. Anaprox, Naprocin).

The usual dosage is two caps every four hours as needed but not more than eight a day or as prescribed by a doctor. The formulation may vary slightly, but it usually has a ratio of 500 mg of acetaminophen to 25 mg of Pamabrom. Excessive and prolonged use of the acetaminophen may cause liver damage, and is not recommended for children 12 years old and younger, and prohibited for children under three years old. Avoid taking two types of medication containing acetaminophen. If redness, swelling or increased pain results from taking the medication, discontinue use immediately and consult the doctor. Ringing in the ears or trouble hearing is also to be taken as danger signs. Avoid activities that may require alertness such as driving as the acetaminophen may induce drowsiness.

Menstrual pain medication containing acetaminophen and parabrom should not be taken if more than three alcoholic drinks is consumed daily, as this may exacerbate possible liver damage. Pregnant and nursing women should only take the medication for pain relief after consulting with a physician. Those allergic to salicylates, i.e. aspirin should avoid these preparations.


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