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Prednisone is a member of the glucocorticoid hormones which are steroidal in nature. Unlike the steroids used by sports persons that are anabolic in nature, prednisone is a catabolic steroid i.e. these types of steroids are meant to break down stored food such as fats, carbohydrates and proteins to produce energy. During the periods of stress, prednisone stimulates the catabolic process in the body in order to overcome the stress. The glucocorticoid hormones are synthesized and secreted by the adrenal cortex. Prednisone can reduce swelling as well as treat many endocrine disorders. In addition to these, prednisone is also used in treating arthritis, severe psoriasis, asthma, lupus, Crohn’s disease as well as ulcerative colitis.

Prednisone is prescribed for which diseases?

Prednisone is used in treating many inflammatory conditions and diseases such as arthritis, psoriasis, allergic reactions, ulcerative colitis, Crohn’s disease, severe asthma, systemic lupus, etc. In addition to this Prednisone is also used in treating lymphomas, leukemia, autoimmune hemolytic anemia as well as idiopathic thrombocytopenic purpura. The main activity of prednisone is to suppress the immune system to reduce inflammatory reactions in the body or to prevent the rejection of transplanted organs by a person’s body. Moreover, prednisone is also used as replacement therapy in patients whose adrenal glands cannot produce sufficient quantity of cortisol.

Side effects of Prednisone: -

There are many side effects of prednisone. Prednisone may lead to deposition of salt in the kidney which might result in excessive thirst and micturition. Excessive use of prednisone drug might cause the adrenal glands to atrophy which can result in reduced synthesis of prednisone by the adrenal cortex. If such a thing happens, the patient might not be able to respond properly during the stressful periods once the medicine is discontinued. Prednisone can even lead to circulatory crisis. As prednisone suppresses the body’s immune responses, latent infections may manifest itself it a more dangerous form which might be difficult to cure. Prednisone hormone can also bring about stomach irritation if administered at a high dose.


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