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Promethazine is a prescription drug in the United States, but is an over the counter (OTC) medication in the UK and Switzerland. Brand names for Promethazine include Phenergan, Promethegan, Romergan, and Fargan.

Promethazine has been and is currently being used to treat a variety of different ailments.

Promethazine has been used as an antihistamine and an antiemetic medication. It has strong sedative or hypnotic effects on patients. Years ago, Promethazine was used as an antipsychotic. It is not currently used for this purpose today. It is being administered as a sedative prior to surgery as well. This helps to counteract the nausea many patients feel after receiving narcotic drugs before and during surgery. Promethazine can be used to treat hay fever or other allergic reactions. It is most often prescribed in conjunction with decongestants such as pseudo-ephedrine. Promethazine works well to treat allergy symptoms such as sneezing, itchy or watery eyes, hives or skin rashes. When combined with codeine, or dextromethorphan, it helps the body to fight a cough. Many people have been prescribed Promethazine combined with Ephedrine or Pseudo ephedrine to combat motion or seasickness. Promethazine has also been administered to pregnant women to combat severe morning sickness. Promethazine combined with the codeine in prescription cough syrup is often used as a recreational drug.

Early signs of serious side effects should be reported to your doctor immediately. Call your doctor if you experience uncontrollable movements of the Eyes, Lips, Tongue, Face, Arms, or Legs. Signs of an overdose of Promethazine include severe drowsiness, dry mouth, shallow breathing or difficulty breathing, fainting, vomiting, dilated pupils, dizziness, flushing of the skin, and nausea. Side effects of Promethazine may impair your thinking and reactions. Alcohol can increase these side effects, so be careful when driving.

This medication may cause harm to an unborn baby, so if you are pregnant, talk to your doctor before taking Promethazine. Elderly patients taking this medication may be very sensitive to the side effects.


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